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HGH Thailand mankhwala - Nkhani pa kukula hormone

HGH (somatotropin) ku Thailand

Hormone yokula (somatotropin) - otchuka kwambiri pakati pa othamanga, okonza thupi ndi alendo ena ku Thailand, ndi wothandizira mankhwala. Poyamba, monga anabolic, somatotropin ankagwiritsidwa ntchito kokha kumangirira thupi, kulemera kwa masewera ndi masewera ena okhudzana ndi kukula kwa minofu, othamanga tsopano, ochita masewera olimbitsa thupi ndi oimirira masewera a masewera amagwiritsira ntchito molimbika kuposa opanga thupi.
Somatotropin inali chida chabwino cha kupirira kuwonjezereka, kutsimikiziridwa bwino pa chithandizo cha kuvulala. Choncho, kukula kwa mankhwalawa kumakula nthawi zonse. Pamapeto pake, mwaluso, pogwiritsa ntchito mankhwalawa, mukhoza kukulitsa kukula kwa wothamanga wachinyamata, ndipo izi ndizofunikira komanso zoyenera kuyankhula.

HGH Thailand
Nchifukwa chiyani thupi likufunikira hormone yowonjezera (HGH)? Soma amatanthauza thupi. Somatotropic amatanthauza kukhala "otentha" - chiyanjano cha thupi. Pakukula kwa thupi, somatotropin ndilo kukula kwakukulu. Kukula kwa thupi kumadalira molingana ndi kuchuluka kwake, m'litali ndi m'lifupi. Kuwonjezera pa somatotropin m'thupi, munthu amakula kwambiri.
Pambuyo pa kukula kwa mafupa a mafupa a mafupa, kukula kwa mafupa kumatalika kumatha, kwa kanthawi kulibe kukula kwa mafupa mu makulidwe. M'madera ena a mafupa, malo akukula sakhala ossification mu moyo wa munthu. Mbali zoterezi zikupezeka mu nsagwada, mphuno, manja ndi mapazi.
Nthawi zina zimachitika chifukwa cha zifukwa zosiyanasiyana ali wamng'ono

Kuchepetsa mphamvu ya kukula kwa hormone kumawonjezeka kwambiri. Kenaka kukula zimphona, zomwe nthawi zina zimafika kutalika kwa 2 m. Matendawa amawoneka ngati matenda ndipo amatchedwa "gigantism." Anthu ambiri padziko lapansili, angakhale okondwa kuti asakhale ziphona, koma anthu apamwamba. Makolo ambiri amafuna kuwonjezera kukula kwa ana awo, ndipo tsopano n'zotheka kale.

Mwa njira, munthu wamtali kwambiri yemwe anakhalapo pa Dziko lapansi, anali ndi kuwonjezeka kwa 2 m 48 masentimita (!). Nthawi zina kutseka kwa hormone kukula kumawonjezeka kale mu thupi lachikulire, pamene ambiri mwa malo okula amakhala atatsekedwa kale. Pankhaniyi, nsagwada, mphuno, manja ndi mapazi zimakula kwambiri. Matendawa amatchedwa acromegaly, mwachitsanzo, kuwonjezeka kwa ziwalo za thupi. Mu munthu wamkulu komanso wapanga thupi, somatotropin imapanga ntchito za anabolic.

Ndiyetu imayambitsa ndondomeko ya mapuloteni m'magulu onse ndi ziphuphu popanda kupatulapo. Ndi anthu ochepa okha amene amadziwa kuti HGH kuphatikizapo zonse zimakhalanso ndi mahomoni opanikizika. Pansi pazipsinjo, magazi amagazi amagazi amakula mwamphamvu, ndipo izi zimathandiza thupi kuti lizigwirizana ndi vutoli mwa kuwonjezera mapuloteni, makamaka mu mphamvu zamagulu.

Choncho, anthu omwe ali ndi malamulo amphamvu omwe ali ndi mafupa abwino kwambiri amalekerera bwino ndi zovuta zosiyanasiyana ndi zovuta za moyo wathu. Amathandizidwa mu izi ndi somatotropin. Popeza kukula kwa nsagwada, mphuno, manja ndi mapazi sizikutsekedwa, "magawo" amenewa amakula m'moyo wonse. Koma ngakhale atakalamba amakula pang'ono, pafupifupi ndi 5-8 mm.

Komabe, paliponse, ndi zina zawo, munthu wopuma pantchito, mphuno ndi ziphuphu zimafika kukula kokongola, komwe kumakhala ngati chizoloŵezi cha nthabwala pozungulira. Kuphunzira kwakukulu ku Thailand kwasonyeza kuti atatha kukwanitsa ali wamng'ono, munthuyo pa moyo wotsatira amakhalabe "akukula" pang'ono. Koma kukula uku kuli kochepa kwambiri. Pofika zaka za 60, munthu amakula 8-10 mm kutalika ndi kukula kwake.

Kukula uku, komabe, sikuwoneka chifukwa cha kugwedeza ndi kufooka kwa minofu, yomwe ikufika m'badwo uwu mwa anthu ambiri. Chifukwa chosowa kukula kwa mahomoni mu ubwana, anthu amakula kwambiri, ndipo amachedwa kutchuka. M'chinenero cha madokotala, matendawa amatchedwa "hypophysial nanism." Pamaso pa kuchepa kwa kukula kwa hormone munthu wamkulu wamkulu kukula, mitundu yosiyanasiyana ya kuperewera kwa thupi imayamba, yomwe nthawi zina imatha kufa, koma imakhala yochepa kwambiri. Mwiniwake, dzina lakuti "hypophysial nanism" kale likusonyeza kuti somatotropin imapangidwa mu chikoka cha pituitary.

Kodi chikoka cha pituitary tsopano chidziwa zonse kapena pafupifupi zonse. Chithokomiro chotchedwa pituitary gland ndi chocheperapo cha ubongo, chomwe chimachokera pansi pa ubongo. Maonekedwe ndi kukula kwa chigoba cha pituitary chikufanana ndi chitumbuwa. Mtundu wa pituitary umatetezedwa bwino chifukwa cha mphamvu zake zochepa.

Ali mu thumba lamphamvu - fupa la "Turkey" pamunsi mwa chigaza. M'matumbo ena amatha kutulutsa mahomoni otulutsa chithokomiro (okhudza chithokomiro), adreno corticotropic (amachititsa kuti adrenal gland), gonadotropic (amachititsa kuti tizirombo toyambitsa matenda), ndi ena.

Ntchito ya pituitary imayendetsedwa ndi hypothalamus, malo apadera a midbrain. Kumeneko, ufulu wowonjezera ndi maulamuliro akukambidwa. Mahomoni otchedwa somatotropic, somatoliberin ndi somatostatin ndi ofunika. Somatoliberin hypothalamus imapangitsa kuti maselo a mphutsi ayambe kusungunuka ndi chifuwa cha pituitary. Somatostatin, mmalo mwake, imalepheretsa kupanga somatotropin. Ngati tikufuna kuchulukitsa kuchuluka kwa hormone m'thupi, ndiye kofunika kuti muwonjezere kuchuluka kwa somatoliberin, kapena kuchepetsa kuchuluka kwa somatostatin.

Kwa nthawi yaitali ankakhulupirira kuti hormone ya kukula imatha kugwira ntchito minofu ya minofu, khungu komanso ziwalo. Patapita nthawi, izi sizinali choncho. HGH imatha kuwonetsa maselo okha mu vitro mu nthawi ya 2,000 nthawi zopitirira thanzi. Mu thupi lachibadwa, HGH imachita pachiwindi.

Chiwindi chimapangitsa kuti thupi likhale ndi mphamvu yotulutsa insulini, yomwe imatchedwanso somatomedin. Somatomedin - imakhalanso ndi anabolic ndi kukula kwa maselo, kumakhudza maselo omwe amawamasulira. Monga kachipatala, nthawi zambiri ndimawona milandu ikadwala matenda a chiwindi, mwanayo amasiya kukula ndipo chikhalidwe chomwecho chimachitika pituitary nanism, ngakhale kuti matendawa amayamba chifukwa cha kusowa kwa somatomedine.

Kumbali ina, acromgaly ndi yofala ndi shuga wabwino mu magazi. Nthendayi muyiyi imayambitsidwa ndi msinkhu wambiri wa somatomedine m'magazi. Kawirikawiri, mndandanda wa malamulo a anabolism ndi hormone ya somatotropic yomwe imagwiritsidwa ntchito ku mafupa a mafupa ndi awa:

 

Ngati tikufuna kukhala ndi zotsatira za anabolic, nenani, pa maselo a minofu, ndiye tikhoza:
1. Kuwonjezera kuchuluka kwa somatoliberin mu hypothalamus.
2. Pezani kuchuluka kwa somatostatin.
3. Lowani mu thupi STG.
4. Tsezani mu thupi somatomedin.
Pazochitika zonsezi, zotsatira zomaliza zidzakwaniritsidwa. Ndipo mukhoza kupita njira imodzi yofotokozera chinthu chofunikira kuchokera kunja, komanso njira yopititsira patsogolo ntchito yakeyo. Mukhozabe kupita panjira yowonjezera
kukhudzidwa kwa maselo ndi zakudya zofunikira, koma kukambirana kumeneku kudzabweranso. Tiyeni tiwone bwino kwambiri mndandanda wonse wa lamulo la somatotropin

ndipo yambani mankhwalawa ndi somatotropin.Akatha zonse, mu mbiri yakale, zonsezi zinayamba ndi izo. STG ndi hormone ya peptide. Amakhala ndi amino acid okwanira yaitali omwe ali ndi 191 amino acid zatsalira. Poyamba 1921, physiologists mu kuyesa zinyama anachotsa gigantism kuyesa pamene anatulutsa kuchotsa zopanda pake wa lobe anterior ya ziweto zoweta zizindikiro. Monga tikuonera, kuthekera kwa kuwonjezeka kwa kukula kwa thupi laling'ono kwawonetsedwa kwa nthawi yaitali kale.

Kuyeretsedwa koti nyama yamtundu wotchedwa somatotropin inali yoyamba yodziwika mu 1944, uman - mu 1956. Ngakhale apo, mothandizidwa ndi STH, amamwali omwe amakhala ndi zotsatira zabwino nthawi zonse amayamba kupatsidwa mphamvu ndi mphamvu. Pambuyo pake, adapezeka kuti pali mitundu itatu ya STH yosiyana ndi maselo olemera. Kwa anthu, STH imapangidwa m'maselo otchedwa eosinophilic maselo a pituitary gland.

Mu zotupa za maselo osakanikirana, monga lamulo, zizindikiro za gigantism zimakula pamene kukula kwaumunthu kuli kwakukulu kuposa 2 m. Panthawi imeneyi ya chitukuko cha mankhwala, zotupa zoterezo zimachiritsidwa bwino mthupi komanso mwachangu. Kukula kwakukulu, komabe kumakhalabe. Pakati pa ochita masewera a basketball padziko lonse, pali anthu ambiri omwe anachitidwa opaleshoni yopanda chithandizo ali wamng'ono.

Chotupacho chimachotsedwa pamphuno (!), Ndipo munthuyo amakhala, ngati kuti palibe chomwe chinachitika. Komabe, pali milandu yosagwiritsidwa ntchito. Kumbali ina, chiwerengero cha osewera "okalamba" akukula, omwe adakali ndi kachilombo koyambitsa kukula kwa hormone.

Kutseka kwa hormone kukula mu magazi ndi pulsed. Patsiku liripo, monga lamulo, 6-9 mapiri akuluakulu. Chiwerengero cha mapiriwa nthawi zina chimakafika ku 12. Kutalika kwa mapiri kumaphatikizapo ndi masewera olimbitsa thupi komanso pogona. Pamadyerero, kutalika kwa mapiri a kutulutsidwa kwa somatotropin, mmalo mwake, kumachepetsanso, makamaka ngati chakudya ndi chakudya.

STG ya zinyama zonse ziri ndi mtima umodzi womwe umagwira ntchito. Mitundu ya m'magazi ya m'munsi imapanga ma GGG apamwamba, koma STG ya mitundu yochepa siimagwira mitundu yambiri yapamtundu. Mwachitsanzo, mtundu wa STG umagwira ntchito pa zinyama zamtundu uliwonse, koma palibe nyama iliyonse ya munthu yomwe imayambira pamtotropin.

Ng'ombe za STG zidzachita zinyama zosavuta kwambiri, koma osati kwa anthu. STG ya whale idzachitanso kanthu pa zinyama za gulu laling'ono, koma osati pa munthu kapena mbulu, ndi zina zotero.


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